Human Cortex

The first phase of this project has completed and includes ISH data for approximately 1000 genes in both visual cortex and temporal cortex from non-diseased adult male and female subjects. Genes in this dataset comprise several categories of broad scientific and clinical interest: cortical cell type markers, disease-related genes, genes identified from comparative genomics literature, and gene families important to neural function such as ion channels, G-protein-coupled receptors, and transporters.

The second phase of this study has begun and includes a focused set of genes in the dorsolateral prefrontal cortex (DLPFC) across a larger cohort. In the current release, gene expression data in the DLPFC is available in non-diseased subjects. Future release will contain data for this brain region in schizophrenic subjects.

Additional information regarding tissue samples and methodology, FAQ, people and organizations who have contributed to this project, and the project application can be accessed under the Human Cortex project tab.